2024-02-01
Brussels, Belgium
This training aims at providing state-of-the-art knowledge on the recent developments in toxicological hazard and risk assessment, with an emphasis on the application in food safety. A limited number of lectures will provide insight in these developments, emphasizing the role of so-called new approach methodologies (NAMs).
2024-04-09 – 2024-04-12
Leuven, Belgium
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Aim
This training aims at providing state-of-the-art knowledge on the recent developments in toxicological hazard and risk assessment, with an emphasis on the application in food safety. A limited number of lectures will provide insight in these developments, emphasizing the role of so-called new approach methodologies (NAMs). In 2016, an ILSI Expert Group published a paper where a flow sheet illustrated the role of different aspects of the process of risk or safety assessment and thereby avoiding the use of animal models. Integrating these aspects, ranging from interpreting knowledge on the chemistry of compounds (and mixtures), exposure, in vitro toxicity and kinetic behaviour, may result in the possibility to predict safety. Course participants will apply the presented flow sheet for a selection of food ingredients in case studies. During the 2-day in person training, a manuscript will be drafted to publish the results of the case studies; participants have the option to be co-author of this publication. Participants are welcome to test the flow sheet on their own data.
Trainers
Prof B. Blaauboer, University of Utrecht, NL
Prof M. Vinken, Free University Brussels, BE
Target participants
Open to all industry experts involved in toxicological risk assessment of compounds, mainly but not exclusively of compounds in food or food ingredients.
Lectures
• General overview of hazard and risk assessment procedures, past and future.
• Cytotoxicity, how to measure it and how to interpret it.
• Understanding mechanisms of action of toxicity: Adverse Outcome Pathways.
• Understanding the kinetic behaviour of chemicals in biological systems (in vitro as well as in vivo): short intro in Physiologically-based kinetic modelling (PBK).
• Quantitative In Vitro-In Vivo extrapolation (QIVIVE).
Registration and cost
• ILSI Europe member: 2.000€
• Non-member: 2.500€
Register here before 15th December.
[post_title] => Advancements in toxicological hazard and risk Assessment for food safety: exploring new approach Methodologies and predictive models
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About
Food system activities are increasing putting pressure on planetary boundaries and the natural resource base which underpins food security for all. They are also accentuating the triple burden of malnutrition for many, and healthier diets derived from more sustainable food systems are needed. The triple 'Cs' of climate, covid and conflict, and other recent short-term shocks to the food system, have emerged against a background of longer-term stresses, adding the issue of food system resilience to the already-recognised sustainability agenda. There is therefore an urgent need for food system change both to improve health and environmental outcomes in fairer and more equitable ways, and to enhance resilience to further shocks and stresses. Building on the momentum from the UN Food System Summit and recognizing that the 2030 target year of the Sustainable Development Goals is on the horizon, this 5th Global Food Security Conference will bring together science, business and policy to address this need.
Themes include:
- Towards net zero
- Enhancing sustainability and resilience of food systems
- Challenges of the true cost of producing food
- Models and applied methodologies to study food systems dynamics and trade-offs
- Ensuring equity and fairness across food systems
- Food politics, governance and accountability of food system actors
- Addressing changing dietary demands and inequities in an interconnected world
- Novel food sources and technologies: Upscaling and acceptability
- The future of farms, farmers and farming
- Robust sustainable food systems to reduce losses and food waste
Info and registration
Find the programme and register here.
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Aim
This training aims at providing state-of-the-art knowledge on the recent developments in toxicological hazard and risk assessment, with an emphasis on the application in food safety. A limited number of lectures will provide insight in these developments, emphasizing the role of so-called new approach methodologies (NAMs). In 2016, an ILSI Expert Group published a paper where a flow sheet illustrated the role of different aspects of the process of risk or safety assessment and thereby avoiding the use of animal models. Integrating these aspects, ranging from interpreting knowledge on the chemistry of compounds (and mixtures), exposure, in vitro toxicity and kinetic behaviour, may result in the possibility to predict safety. Course participants will apply the presented flow sheet for a selection of food ingredients in case studies. During the 2-day in person training, a manuscript will be drafted to publish the results of the case studies; participants have the option to be co-author of this publication. Participants are welcome to test the flow sheet on their own data.
Trainers
Prof B. Blaauboer, University of Utrecht, NL
Prof M. Vinken, Free University Brussels, BE
Target participants
Open to all industry experts involved in toxicological risk assessment of compounds, mainly but not exclusively of compounds in food or food ingredients.
Lectures
• General overview of hazard and risk assessment procedures, past and future.
• Cytotoxicity, how to measure it and how to interpret it.
• Understanding mechanisms of action of toxicity: Adverse Outcome Pathways.
• Understanding the kinetic behaviour of chemicals in biological systems (in vitro as well as in vivo): short intro in Physiologically-based kinetic modelling (PBK).
• Quantitative In Vitro-In Vivo extrapolation (QIVIVE).
Registration and cost
• ILSI Europe member: 2.000€
• Non-member: 2.500€
Register here before 15th December.
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