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ILSI Europe developed a series of three publications that examine the intestinal barrier, its role in health and disease, and the potential impact of probiotics on function.

Homeostasis of the Gut Barrier and Potential Biomarkers
American Journal of Physiology – Gastrointestinal and Liver Physiology
Wells et al. 2016
The authors describe the role of different mechanisms and interactions that support the maintenance of intestinal barrier function. They also discuss biomarkers in blood, feces, or urine that can be used to assess intestinal permeability and epithelial integrity.

Available online: Gut Barrier and Biomarkers

Human Intestinal Barrier Function in Health and Disease
Clinical and Translational Gastroenterology
König et al., 2016
The authors discuss the role of intestinal permeability in common disorders.

Available online: Intestinal Barrier in Health and Disease

Can probiotics modulate human disease by impacting intestinal barrier function?
British Journal of Nutrition
Bron et al., 2017
The author investigate available evidence for the role of probiotics in epithelial integrity.

Available online: Probiotics and Intestinal Barrier Function

 Contact ILSI Europe for information about is activities on the human microbiome: info@ilsieurope.be