Advance Consumer Health through Bioactive Compounds
- Explore strategies to ensure the safe and effective use of bioactive compounds in products and formulations.
- Learn how bioactive compound research can enhance consumer benefits and overall health.
- Discover how quantified intake recommendations can improve consumer messaging and raise awareness of the potential health benefits of particular products and formulations.
- Understand the role of bioactive compounds in nutrition and how they can support better guidance for practitioners and consumers.
Don’t miss this opportunity to gain valuable insights that can improve both your consumer messaging and the health impact of your products.
Work with ILSI U.S. and Canada to improve consumer health and well-being by fostering safer and more effective uses of bioactive compounds, functional foods, and supplements in your products and formulations.
Session 8 – Bioactive Compounds: Safety, Benefits, and Evidence-Based Guidance
Wednesday, April 9, 2025 | 4:00 – 5:30 p.m.
The Lineup You Won't Want to Miss:
Session Co-Chairs:
- April Stull, PhD, RDN, FAND, Baylor University, USA
- Marissa Kuehn, Amway, USA
Speakers and presentations:
- Framework for establishing recommended intakes for bioactive compounds – Janet Novotny, PhD, USDA, USA
- Case Study: Establishing Dietary Guidance for Lutein – Elizabeth Johnson, PhD, Friedman School of Nutrition Science and Policy, Tufts University, USA
- Industry perspective – Andrew Shao, PhD, Chromadex, USA
Case Study: Establishing Dietary Guidance for Lutein – Elizabeth Johnson, PhD, Friedman School of Nutrition Science and Policy, Tufts University, USA
Abstract: It has been 11 years since Lupton et al. (Eur J Nutr, 2014) proposed criteria for a bioactive to qualify for evaluation for dietary guidance. These criteria are: 1) a commonly used definition for the bioactive; 2) a method for analyzing the bioactive which is consistent with the definition; 3) a database for the amount of the bioactive in foods; 4) prospective cohort studies on health outcomes; 5) clinical trials on digestion, absorption, activation, transport, excretion; 6) clinical trials on efficacy and dose response; 7) safety data at the level of intake; 8) systematic reviews/meta-analyses on efficacy; and 9).a plausible biological explanation for efficacy. An evaluation of lutein using these criteria warrants consideration for guidance on intake.
Elizabeth J. Johnson, Ph.D. obtained her Ph.D. in nutritional biochemistry at the University of Wisconsin-Madison. Her postdoctoral work was conducted at the Jean Mayer USDA Human Nutrition Center on Aging at Tufts University where she began clinical studies on research on human metabolism of carotenoids. She currently has a faculty appointment at the Friedman School of Nutrition Science & Policy at Tufts University. She has over 35 years of experience in the study of nutrition and healthy aging with an emphasis on carotenoids and age-related visual and cognitive function and has over 100 peer-reviewed publications of which more than sixty are on the topic of carotenoids. She is a member of the International Carotenoid Society. Other memberships include the American College of Nutrition, Carotenoid Research Interactive Group, American Society for Nutrition, and the Brain and Ocular Nutrition Group. Dr. Johnson also has editorial roles at The Journal of Nutrition, Nutrients and Journal of Nutrition in Gerontology and Geriatrics.