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Best Practices for the Conduct of Animal Studies to Evaluate Crops Genetically Modified for Input Traits


Task Force #5

Abstract: The purpose of this document is to recommend guidelines for the production, harvest, sampling, and analysis of GM plants containing input traits (i.e., insect protection, herbicide tolerance, virus resistance) and for the conduct of animal experiments using these plants. The rationale for this project was to provide a platform that could serve as the basis for the international harmonization of study protocols for livestock and poultry performance. This publication should be a good reference for animal scientists worldwide in academia, industry, and government desiring to conduct studies with livestock and poultry fed GM crops and their byproducts. In preparing this document, scientists with expertise in areas such as animal nutrition (various farm animal species and poultry), health, feed chemistry, statistics, and other relevant disciplines developed a process whereby guidelines were developed under the leadership of ILSI in collaboration with the Federation of Animal Science Societies. The authors decided that the study guidelines for each animal species should be written as a stand-alone procedure to simplify their use.

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References

Chapter 1: Introduction

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Chapter 2: Production, Handling, Storage, and Processing of Crops

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Chapter 3: Sampling and Analysis of Harvested and Processed Crop Material

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Chapter 4: Protocols for Evaluating Feedstuffs with Genetically Modified Input Traits: Poultry Meat Production

  • FASS (Federation of Animal Science Societies) (1999) Guide for the care and use of agricultural animals in agricultural research and teaching. FASS, Savoy, IL
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Chapter 5: Protocols for Evaluating Feedstuffs with Genetically Modified Input Traits: Poultry Egg Production

  • FASS (Federation of Animal Science Societies) (1999) Guide for the care and use of agricultural animals in agricultural research and teaching. FASS, Savoy, IL
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Chapter 6: Protocols for Evaluating Feedstuffs with Genetically Modified Input Traits: Swine

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  • FASS (Federation of Animal Science Societies) (1999) Guide for the care and use of agricultural animals in agricultural research and teaching. FASS, Savoy, IL
  • Fuller MF (ed) (1991) In vitro digestion for pigs and poultry. CAB International, Wallingford, United Kingdom
  • Gabert VM, Jørgensen H, Nyachoti CM (2001) Bioavailability of amino acids in feedstuffs for swine. In Lewis AJ, Southern LL (eds), Swine nutrition. CRC Press, Boca Raton, FL, pp 151-186
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Chapter 7: Protocols for Evaluating Feedstuffs with Genetically Modified Input Traits: Lactating Dairy Cows

  • FASS (Federation of Animal Science Societies) (1999) Guide for the care and use of agricultural animals in agricultural research and teaching. FASS, Savoy, IL
  • NRC (National Research Council) (2001) Nutrient requirements of dairy cattle, 7th ed. National Academy Press, Washington, DC LINK

Chapter 8: Protocols for Evaluating Feedstuffs with Genetically Modified Input Traits: Growing and Finishing Ruminants

  • AOAC Official Methods of Analysis 17th ed. (2000) AOAC INTERNATIONAL, Gaithersburg, MD LINK
  • FASS (Federation of Animal Science Societies) (1999) Guide for the care and use of agricultural animals in agricultural research and teaching. FASS, Savoy, IL
  • NRC (National Research Council) Update (2000) Nutrient requirements of beef cattle. National Academy Press, Washington, DC LINK
  • NRC (National Research Council) (1985) Nutrient requirements of sheep, National Academy Press, Washington, DC LINK

Chapter 9: Statistical Analysis and Interpretation of Results

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