ILSI entities around the world publish scientific research articles, literature reviews, gap analyses, and meeting proceedings in peer-reviewed journals and publications. Our research has a flawless track record. In fact, not one of the 1,000+ articles ILSI has published since our organization's founding has ever been retracted.
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ILSI's Research Library:
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Migration and Changing Patterns of Oral Health
1996
Migration of Novel Offset Printing Inks From Cardboard Packaging Into Food
2009
Food Additives and Contaminants: Part A. 2009;26(12):1574-1580.
Migressives: A Research Project on Migration From Adhesives in Food-Packaging Materials in Support of European Legislation and Standardization
2009
Food Additives and Contaminants: Part A. 2009;6(12):1581-1591.
Mineral Biofortification Strategies for Food Staples: The Example of Common Bean
Journal of Agricultural and Food Chemistry, 2013
Proceedings from the 2012 IFBiC Plant Compositional Analysis Workshop, published in the Journal of Agricultural and Food Chemistry (Blair et al. 2013;61(35):8287-8294).
Mineral oil risk assessment: Knowledge gaps and roadmap. Outcome of a multi-stakeholders workshop
Trends in Food Science & Technology, 2021
Commissioned by the Process-Related Compounds & Natural Toxins and the Packaging Materials Task Forces.
- the lack of validated and standardized analytical methods for relevant food matrices, and
- gaps in assessing the risk for consumers' health.
The consensus is that the lack of standardized, validated analytical methods able to assure good inter-laboratory reproducibility is the main gap underlining most of the existing difficulties to understand MOH.
In order to conduct adequate substance identification and quantification for input into risk assessment, the need for confirmatory methods that provide a detailed characterization of the unresolved complex mixtures needs to be solved.
The limited number of surveys covering a wide range of foods and enough samples to detect major sources of contamination other than packaging in paperboard also hinders reliable exposure estimation.
Decision tree to identify auxilary methods. (Adapted from Bratinova & Hoekstra, 2019)
Industry sectors represented in the workshop
- Food & Drink
- Mineral Oil/Waxes
- Testing Laboratories
- Analytical Instruments
- Food Contact Materials
- Cosmetics
- Petroleum
Read the full-text article here
Scientific abstract Expand BackgroundIn recent years there have been significant advancements in the understanding of mineral oil hydrocarbons (MOH) in foods and their potential risk to health. However, important gaps in knowledge remain, such as the lack of validated and standardized analytical methods for relevant food matrices and gaps in assessing the risk for consumers' health. Scope & approach
A workshop was organized by the European Branch of the International Life Science Institute to identify knowledge gaps in analytical methods, assessment of exposure, hazard characterisation, and risk assessment of MOH. This work captures the outcome of the workshop and builds upon it by combining the perspectives of the participants with an updated review of the literature to provide a roadmap for future management of the topic. Key findings and conclusions
Most participants to the workshop agreed that the key issue underlying many of the knowledge gaps in the field of MOH risk analysis and management is the lack of standardized, validated analytical methods able to assure good inter-laboratory reproducibility and to enable understanding of MOH occurrence in foods. It has been demonstrated that method EN 16995 used for MOH determination in vegetable oils and fats is not reliable below 10 mg/kg of food. There is also a need for confirmatory methods that provide a detailed characterization of the unresolved complex mixture observed from one-dimensional chromatographic methods. This is required to enable adequate substance identification and quantification for input into risk assessment. A major gap in the exposure estimation is the limited number of surveys covering a wide range of foods and enough samples to detect major sources of contamination other than packaging in paperboard. Data on concentration of MOH fractions in human body needed to determine internal exposure estimates is scarce. Data relating concentration in tissues with personal data, lifestyle, food intake and the use of cosmetics are needed to clarify the complex system of distribution of MOSH in the body and to possibly establish relationship between external and internal exposure. Additional toxicological studies to better characterize the hazards of relevant MOH are required for a better human health risk assessment. Keywords Expand
Mineral oil hydrocarbon, Risk assessment, Exposure assessment, Food contaminant, MOSH, MOAH
Number of participants in the workshop 61 from Academica, Public organisations, and Industry. EN 16995 used for MOH determination in vegetable oils and fats is not reliable below 10 mg/kg of food. Main indetified gaps in the knowledge of Mineral Oil Hydrocarbons 8To enable human risk assessment, the performance of toxicological studies on the relevant MOH mixtures and possibly their components is required.
This work was conducted in collaboration with the Packaging Materials Task Force.
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