Research Library: Scientific Articles, Monographs, and More

ILSI entities around the world publish scientific research articles, literature reviews, gap analyses, and meeting proceedings in peer-reviewed journals and publications. Our research has a flawless track record. In fact, not one of the 1,000+ articles ILSI has published since our organization's founding has ever been retracted.

In addition, ILSI publishes books, monographs, white papers, and newsletters. Our commitment to the highest scientific standards and our adherence to rigorous scientific principles demonstrate ILSI's integrity in research.

ILSI's Research and Scientific Articles

Browse ILSI's research publications, including the latest findings and in-depth analyses that contribute to advancing knowledge in the nutrition, food safety, sustainability, and health fields. Whether you're a fellow researcher, a student, or simply curious, our scientific articles provide valuable insights into the work that drives innovation and discovery.

Below, our publications are listed by publication date, from the newest article to the oldest. You can also filter the list by title or publication type.

ILSI's Research Library:

All Publications

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Abstract

Prebiotics, particularly non-digestible carbohydrates (NDCs), are increasingly recognized for their role in modulating immune responses in the gut, lungs, and urinary tract. This review systematically evaluates evidence from human studies on the effects of NDCs and prebiotics on immune markers, infection risk and severity, inflammation, and vaccine responses. Prebiotics such as inulin, galactooligosaccharides (GOS), and fructooligosaccharides (FOS) positively influence gut microbiota by promoting beneficial species like Bifidobacteria. They also enhance the production of short-chain fatty acids (SCFAs) like butyrate, which interact with immune cells via G-protein-coupled receptors, inducing anti-inflammatory effects. In addition to microbiota-mediated mechanisms, NDCs and prebiotics may directly affect immune and epithelial cells by interacting with pattern recognition receptors (PRRs), enhancing gut barrier function, and modulating immunity. A systematic review of human studies showed that prebiotics, including GOS, FOS, and 2′-fucosyllactose (2FL), reduced infections and increased IgA in healthy infants, while yeast β-glucan reduced respiratory infection symptoms in healthy adults. Yeast β-glucan and GOS supplementation resulted in improvements in NK cell activity. Some effects on vaccine efficacy were noted in young adults, but the overall impact of NDCs and prebiotics on vaccination and systemic inflammation was inconsistent. Further research is needed to clarify the mechanisms involved and to optimize health applications.

 

Keywords

prebiotic; non-digestible carbohydrates; immunity; infection; inflammation; microbiota

Read the full papaer

Commissionned by the Prebiotics Task Force

One-pager

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ILSI SEA Region Malaysia Country Community, Ministry of Health, Malaysia and Institute of Medical Research, Malaysia

Sugar is widely consumed in Malaysia through various foods and beverages, yet limited data in the Malaysian Food Composition Database (MyFCD) has restricted research on its dietary sources. This study analyzed 118 commonly consumed foods identified from the Malaysian Adult Nutrition Survey (MANS) 2014, covering both pre-packaged and traditional items across eight food categories. The findings provide essential updates to the MyFCD and serve as a useful reference to help Malaysians make more informed and healthier food choices.

Read the full publication here.

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