Research Library: Scientific Articles, Monographs, and More

ILSI entities around the world publish scientific research articles, literature reviews, gap analyses, and meeting proceedings in peer-reviewed journals and publications. Our research has a flawless track record. In fact, not one of the 1,000+ articles ILSI has published since our organization's founding has ever been retracted.

In addition, ILSI publishes books, monographs, white papers, and newsletters. Our commitment to the highest scientific standards and our adherence to rigorous scientific principles demonstrate ILSI's integrity in research.

ILSI's Research and Scientific Articles

Browse ILSI's research publications, including the latest findings and in-depth analyses that contribute to advancing knowledge in the nutrition, food safety, sustainability, and health fields. Whether you're a fellow researcher, a student, or simply curious, our scientific articles provide valuable insights into the work that drives innovation and discovery.

Below, our publications are listed by publication date, from the newest article to the oldest. You can also filter the list by title or publication type.

ILSI's Research Library:

Journal Articles

“Guidance Document on Use of Traditional Knowledge in Scientific Evidence-Based Novel Foods and Ingredients”

ILSI India’s Knowledge Centre on Functional Foods, Immunity and Gut Health (K-FFIG) has published a Guidance Document on the Use of Traditional Knowledge in Scientific Evidence-Based Novel Foods and Ingredients”, aimed at enabling the responsible translation of traditional wisdom into validated, safe, and effective food solutions for public benefit.

 The Guidance Document can be downloaded from: https://tinyurl.com/3ey9xpfm

Read more

WP_Query Object
(
    [query] => Array
        (
            [post_type] => publication
            [posts_per_page] => 5
            [type] => 
            [area] => 
            [committee] => 
            [authors] => 
            [showtitle] => 
            [meta_query] => Array
                (
                    [0] => Array
                        (
                            [key] => _ilsi_type
                            [value] => journal-article
                            [compare] => =
                        )

                )

            [tax_query] => Array
                (
                )

            [paged] => 1
            [meta_key] => _ilsi_date
            [orderby] => meta_value
            [order] => DESC
        )

    [query_vars] => Array
        (
            [post_type] => publication
            [posts_per_page] => 5
            [type] => 
            [area] => 
            [committee] => 
            [authors] => 
            [showtitle] => 
            [meta_query] => Array
                (
                    [0] => Array
                        (
                            [key] => _ilsi_type
                            [value] => journal-article
                            [compare] => =
                        )

                )

            [tax_query] => Array
                (
                )

            [paged] => 1
            [meta_key] => _ilsi_date
            [orderby] => meta_value
            [order] => DESC
            [error] => 
            [m] => 
            [p] => 0
            [post_parent] => 
            [subpost] => 
            [subpost_id] => 
            [attachment] => 
            [attachment_id] => 0
            [name] => 
            [pagename] => 
            [page_id] => 0
            [second] => 
            [minute] => 
            [hour] => 
            [day] => 0
            [monthnum] => 0
            [year] => 0
            [w] => 0
            [category_name] => 
            [tag] => 
            [cat] => 
            [tag_id] => 
            [author] => 
            [author_name] => 
            [feed] => 
            [tb] => 
            [meta_value] => 
            [preview] => 
            [s] => 
            [sentence] => 
            [title] => 
            [fields] => all
            [menu_order] => 
             => 
            [category__in] => Array
                (
                )

            [category__not_in] => Array
                (
                )

            [category__and] => Array
                (
                )

            [post__in] => Array
                (
                )

            [post__not_in] => Array
                (
                )

            [post_name__in] => Array
                (
                )

            [tag__in] => Array
                (
                )

            [tag__not_in] => Array
                (
                )

            [tag__and] => Array
                (
                )

            [tag_slug__in] => Array
                (
                )

            [tag_slug__and] => Array
                (
                )

            [post_parent__in] => Array
                (
                )

            [post_parent__not_in] => Array
                (
                )

            [author__in] => Array
                (
                )

            [author__not_in] => Array
                (
                )

            [search_columns] => Array
                (
                )

            [ignore_sticky_posts] => 
            [suppress_filters] => 
            [cache_results] => 1
            [update_post_term_cache] => 1
            [update_menu_item_cache] => 
            [lazy_load_term_meta] => 1
            [update_post_meta_cache] => 1
            [nopaging] => 
            [comments_per_page] => 50
            [no_found_rows] => 
        )

    [tax_query] => WP_Tax_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [table_aliases:protected] => Array
                (
                )

            [queried_terms] => Array
                (
                )

            [primary_table] => wp_posts
            [primary_id_column] => ID
        )

    [meta_query] => WP_Meta_Query Object
        (
            [queries] => Array
                (
                    [0] => Array
                        (
                            [key] => _ilsi_date
                        )

                    [1] => Array
                        (
                            [0] => Array
                                (
                                    [key] => _ilsi_type
                                    [value] => journal-article
                                    [compare] => =
                                )

                            [relation] => OR
                        )

                    [relation] => AND
                )

            [relation] => AND
            [meta_table] => wp_postmeta
            [meta_id_column] => post_id
            [primary_table] => wp_posts
            [primary_id_column] => ID
            [table_aliases:protected] => Array
                (
                    [0] => wp_postmeta
                    [1] => mt1
                )

            [clauses:protected] => Array
                (
                    [wp_postmeta] => Array
                        (
                            [key] => _ilsi_date
                            [compare] => =
                            [compare_key] => =
                            [alias] => wp_postmeta
                            [cast] => CHAR
                        )

                    [mt1] => Array
                        (
                            [key] => _ilsi_type
                            [value] => journal-article
                            [compare] => =
                            [compare_key] => =
                            [alias] => mt1
                            [cast] => CHAR
                        )

                )

            [has_or_relation:protected] => 
        )

    [date_query] => 
    [request] => SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID
					 FROM wp_posts  INNER JOIN wp_postmeta ON ( wp_posts.ID = wp_postmeta.post_id )  INNER JOIN wp_postmeta AS mt1 ON ( wp_posts.ID = mt1.post_id )
					 WHERE 1=1  AND ( 
  wp_postmeta.meta_key = '_ilsi_date' 
  AND 
  ( 
    ( mt1.meta_key = '_ilsi_type' AND mt1.meta_value = 'journal-article' )
  )
) AND ((wp_posts.post_type = 'publication' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled')))
					 GROUP BY wp_posts.ID
					 ORDER BY wp_postmeta.meta_value DESC
					 LIMIT 0, 5
    [posts] => Array
        (
            [0] => WP_Post Object
                (
                    [ID] => 52370
                    [post_author] => 40
                    [post_date] => 2026-04-13 11:28:22
                    [post_date_gmt] => 2026-04-13 15:28:22
                    [post_content] => 
                    [post_title] => What are probiotics?
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => what-are-probiotics
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2026-04-13 11:28:22
                    [post_modified_gmt] => 2026-04-13 15:28:22
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://ilsi.org/publication/what-are-probiotics/
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [1] => WP_Post Object
                (
                    [ID] => 52444
                    [post_author] => 357
                    [post_date] => 2026-06-10 02:20:58
                    [post_date_gmt] => 2026-06-10 06:20:58
                    [post_content] => 
                    [post_title] => “Guidance Document on Use of   Traditional Knowledge in Scientific Evidence-Based Novel Foods and Ingredients”
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => guidance-document-on-use-of-traditional-knowledge-in-scientific-evidence-based-novel-foods-and-ingredients
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2026-06-10 02:20:58
                    [post_modified_gmt] => 2026-06-10 06:20:58
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://ilsi.org/publication/guidance-document-on-use-of-traditional-knowledge-in-scientific-evidence-based-novel-foods-and-ingredients/
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [2] => WP_Post Object
                (
                    [ID] => 52451
                    [post_author] => 358
                    [post_date] => 2026-06-12 10:28:28
                    [post_date_gmt] => 2026-06-12 14:28:28
                    [post_content] => 

	

A Framework for Developing Intake and Use Guidance for Dietary Supplement Bioactives

Dietary bioactives, which are commonly found in food, beverages, and dietary supplements, include nonessential food components that can support health beyond preventing nutrient deficiencies. Despite their known health benefits and potential for adverse effects, there is limited guidance on appropriate intake levels, safety, and efficacy of these ingredients, particularly those present in dietary supplements. This lack of guidance can be challenging for individuals attempting to make informed decisions about products marketed for health benefits. A previously published perspective proposed a 4-step framework for developing quantitative intake recommendations for bioactive constituents in food. This framework addressed bioactive characterization, safety evaluation, efficacy assessment, and how to develop intake levels from foods. However, it did not account for the unique considerations of bioactives consumed in dietary supplement form. The current paper builds on the original framework by addressing the specific factors that must be considered when developing intake guidance for bioactive constituents found in dietary supplements. These include differences in dose, matrix, purity, bioavailability, and intended use. In doing so, this paper aims to advance the development of evidence-based recommendations for supplements, while also highlighting the fundamental distinctions between bioactive constituents delivered through food and diet compared with those delivered through dietary supplements.

[post_title] => Intake and Use Guidance for Dietary Supplement Bioactives [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => a-framework-for-developing-intake-and-use-guidance-for-dietary-supplement-bioactives [to_ping] => [pinged] => [post_modified] => 2026-06-12 10:28:28 [post_modified_gmt] => 2026-06-12 14:28:28 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.org/?post_type=publication&p=52451 [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 52457 [post_author] => 358 [post_date] => 2026-06-15 10:17:02 [post_date_gmt] => 2026-06-15 14:17:02 [post_content] => [post_title] => Intake and Use Guidance for Dietary Supplement Bioactives [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => a-framework-for-developing-intake-and-use-guidance-for-dietary-supplement-bioactives-2 [to_ping] => [pinged] => [post_modified] => 2026-06-15 10:17:02 [post_modified_gmt] => 2026-06-15 14:17:02 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.org/?post_type=publication&p=52457 [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 52234 [post_author] => 351 [post_date] => 2025-11-21 09:39:34 [post_date_gmt] => 2025-11-21 09:39:34 [post_content] =>

Abstract

Background

Early-life exposures might negatively affect fetal and infant development, predisposing children to obesity. This study aimed to systematically identify and evaluate risk factors for childhood obesity in preconception, pregnancy, and infancy, and assess their potential for future prediction and prevention strategies.

Methods

This systematic review (PROSPERO, CRD42022355152) included longitudinal studies from selected electronic databases published between inception and August 17th, 2022, identifying maternal, paternal, or infant risk factors from preconception until infancy for childhood obesity between 2 and 18 years. Screening and data extraction were conducted using standardized forms. We assessed risk factor quality on modifiability and predictive power using a piloted criteria template from ILSI-Europe-Marker-Validation-Initiative.

Findings

We identified 172 publications from observational and five publications from intervention studies involving n = 1,879,971 children from 37, predominantly high-income, countries. Average reported childhood obesity prevalence was 11.1%. Pregnancy and infancy risk factors were mostly studied. We identified 59 potential risk factors; 23 were consistently associated. Strongest risk factors were: higher maternal prepregnancy weight (n = 28/31 publications with positive associations), higher gestational weight gain (n = 18/21), maternal smoking during pregnancy (n = 23/29), higher birth weight (n = 20/28), large-size-for-gestational-age-at-birth (n = 17/18), no breastfeeding (n = 20/31), and higher infant weight gain (n = 12/12). Level of evidence was generally moderate due to unreliable exposure measurement, short follow-up/loss to follow-up, and risk of confounding.

Interpretation

We identified seven early-life risk factors, which were strongly associated with childhood obesity, and can contribute to future prediction and prevention strategies. These findings support the implementation of prevention strategies targeting these risk factors from a clinical and population perspective, where possible integrated with implementation studies.

One pager

Read the full paper

Commissioned by the Early Nutrition and Long-Term Health Task Force

[post_title] => Risk Factors in the First 1000 Days of Life Associated With Childhood Obesity: A Systematic Review and Risk Factor Quality Assessment [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => risk-factors-in-the-first-1000-days-of-life-associated-with-childhood-obesity-a-systematic-review-and-risk-factor-quality-assessment [to_ping] => [pinged] => [post_modified] => 2025-11-21 04:58:19 [post_modified_gmt] => 2025-11-21 09:58:19 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.org/?post_type=publication&p=52234 [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 5 [current_post] => -1 [before_loop] => [in_the_loop] => [post] => WP_Post Object ( [ID] => 52370 [post_author] => 40 [post_date] => 2026-04-13 11:28:22 [post_date_gmt] => 2026-04-13 15:28:22 [post_content] => [post_title] => What are probiotics? [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => what-are-probiotics [to_ping] => [pinged] => [post_modified] => 2026-04-13 11:28:22 [post_modified_gmt] => 2026-04-13 15:28:22 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.org/publication/what-are-probiotics/ [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 597 [max_num_pages] => 120 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => 1 [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => [query_vars_hash:WP_Query:private] => fbb1377d702532f1d039b365997fb088 [query_vars_changed:WP_Query:private] => [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) [query_cache_key:WP_Query:private] => wp_query:b03b253fac78fabdafc6fc6fd425fa8e )