ILSI entities around the world publish scientific research articles, literature reviews, gap analyses, and meeting proceedings in peer-reviewed journals and publications. Our research has a flawless track record. In fact, not one of the 1,000+ articles ILSI has published since our organization's founding has ever been retracted.
In addition, ILSI publishes books, monographs, white papers, and newsletters. Our commitment to the highest scientific standards and our adherence to rigorous scientific principles demonstrate ILSI's integrity in research.
Browse ILSI's research publications, including the latest findings and in-depth analyses that contribute to advancing knowledge in the nutrition, food safety, sustainability, and health fields. Whether you're a fellow researcher, a student, or simply curious, our scientific articles provide valuable insights into the work that drives innovation and discovery.
Below, our publications are listed by publication date, from the newest article to the oldest. You can also filter the list by title or publication type.
ILSI's Research Library:
Publication Date
Journal Articles
ILSI US & Canada Annual Symposium Scientific Report
Nutrition Today , 2025
- ILSI U.S. and Canada
Algorithms to Estimate Bioavailability of Nutrients from Foods
Advances In Nutrition, 2025
- ILSI U.S. and Canada
A step by step process on how to develop bioavailability prediction equations for estimating nutrients in foods
A realidade sobre hormônios em carnes
2025
- ILSI Brasil
Impact of non-digestible carbohydrates and prebiotics on immunity, infections, inflammation and vaccine responses: a systematic review of evidence in healthy humans and a discussion of mechanistic proposals
Critical Reviews in Food Science and Nutrition, 2025
- ILSI Europe
Sugar content in Malaysian foods for updating the Malaysian food composition database
Applied Food Research, 2025
- ILSI Southeast Asia Region
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Abstract
Prebiotics, particularly non-digestible carbohydrates (NDCs), are increasingly recognized for their role in modulating immune responses in the gut, lungs, and urinary tract. This review systematically evaluates evidence from human studies on the effects of NDCs and prebiotics on immune markers, infection risk and severity, inflammation, and vaccine responses. Prebiotics such as inulin, galactooligosaccharides (GOS), and fructooligosaccharides (FOS) positively influence gut microbiota by promoting beneficial species like Bifidobacteria. They also enhance the production of short-chain fatty acids (SCFAs) like butyrate, which interact with immune cells via G-protein-coupled receptors, inducing anti-inflammatory effects. In addition to microbiota-mediated mechanisms, NDCs and prebiotics may directly affect immune and epithelial cells by interacting with pattern recognition receptors (PRRs), enhancing gut barrier function, and modulating immunity. A systematic review of human studies showed that prebiotics, including GOS, FOS, and 2′-fucosyllactose (2FL), reduced infections and increased IgA in healthy infants, while yeast β-glucan reduced respiratory infection symptoms in healthy adults. Yeast β-glucan and GOS supplementation resulted in improvements in NK cell activity. Some effects on vaccine efficacy were noted in young adults, but the overall impact of NDCs and prebiotics on vaccination and systemic inflammation was inconsistent. Further research is needed to clarify the mechanisms involved and to optimize health applications.
Keywords
prebiotic; non-digestible carbohydrates; immunity; infection; inflammation; microbiota
Read the full papaer
Commissionned by the Prebiotics Task Force
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ILSI SEA Region Malaysia Country Community, Ministry of Health, Malaysia and Institute of Medical Research, Malaysia
Sugar is widely consumed in Malaysia through various foods and beverages, yet limited data in the Malaysian Food Composition Database (MyFCD) has restricted research on its dietary sources. This study analyzed 118 commonly consumed foods identified from the Malaysian Adult Nutrition Survey (MANS) 2014, covering both pre-packaged and traditional items across eight food categories. The findings provide essential updates to the MyFCD and serve as a useful reference to help Malaysians make more informed and healthier food choices.
Read the full publication here.
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