ILSI entities around the world publish scientific research articles, literature reviews, gap analyses, and meeting proceedings in peer-reviewed journals and publications. Our research has a flawless track record. In fact, not one of the 1,000+ articles ILSI has published since our organization's founding has ever been retracted.
In addition, ILSI publishes books, monographs, white papers, and newsletters. Our commitment to the highest scientific standards and our adherence to rigorous scientific principles demonstrate ILSI's integrity in research.
Browse ILSI's research publications, including the latest findings and in-depth analyses that contribute to advancing knowledge in the nutrition, food safety, sustainability, and health fields. Whether you're a fellow researcher, a student, or simply curious, our scientific articles provide valuable insights into the work that drives innovation and discovery.
Below, our publications are listed by publication date, from the newest article to the oldest. You can also filter the list by title or publication type.
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Evaluating the consistency of judgments derived through both in silico and expert application of the Cramer classification scheme
2024
- ILSI Europe
The Cramer classification scheme has emerged as one of the most extensively-adopted predictive toxicology tools, owing in part to its employment for chemical categorisation within threshold of toxicological concern evaluation. The characteristics of several of its rules have contributed to inconsistencies with respect to degree of hazard attributed to common (particularly food-relevant) substances. This investigation examines these discrepancies, and their origins, raising awareness of such issues amongst users seeking to apply and/or adapt the rule-set.
A relação entre a alimentação e o ganho de massa muscular: mitos e dicas
2024
- ILSI Brasil
The Role of Complementary Feeding Practices in Addressing the Double Burden of Malnutrition among Children Aged 6–23 Months: Insight from the Vietnamese General Nutrition Survey 2020
Nutrients, 2024
- ILSI Southeast Asia Region
This study examined the demographic and socioeconomic determinants of IYCF practices, and their impacts on the DBM among 2039 Vietnamese children aged 6–23 months from the General Nutrition Survey 2020.
Consenso do ILSI Brasil sobre vegetarianismo nos primeiros cinco anos de vida: repercussões na saúde, manejo e recomendações
2024
- ILSI Brasil
Síndrome látex-fruta: entenda o que é a alergia alimentar provocada pela presença de proteínas semelhantes às encontradas nas seringueiras
2024
- ILSI Brasil
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Abstract
The Cramer classification scheme has emerged as one of the most extensively-adopted predictive toxicology tools, owing in part to its employment for chemical categorisation within threshold of toxicological concern evaluation. The characteristics of several of its rules have contributed to inconsistencies with respect to degree of hazard attributed to common (particularly food-relevant) substances. This investigation examines these discrepancies, and their origins, raising awareness of such issues amongst users seeking to apply and/or adapt the rule-set.
A dataset of over 3000 compounds was assembled, each with Cramer class assignments issued by up to four groups of industry and academic experts. These were complemented by corresponding outputs from in silico implementations of the scheme present within Toxtree and OECD QSAR Toolbox software, including a working of a "Revised Cramer Decision Tree". Consistency between judgments was assessed, revealing that although the extent of inter-expert agreement was very high (≥97%), general concordance between expert and in silico calls was more modest (∼70%). In particular, 22 chemical groupings were identified to serve as prominent sources of disagreement, the origins of which could be attributed either to differences in subjective interpretation, to software coding anomalies, or to reforms introduced by authors of the revised rules.
This work was commissioned by the Threshold of Toxicological Concern (TTC) Task Force. For more information, click here.
Read the full article here
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[post_title] => A relação entre a alimentação e o ganho de massa muscular: mitos e dicas
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In collaboration with University of Leeds, UK, and National Institute of Nutrition (NIN), Vietnam
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Click here to view the full publication.
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Abstract
The Cramer classification scheme has emerged as one of the most extensively-adopted predictive toxicology tools, owing in part to its employment for chemical categorisation within threshold of toxicological concern evaluation. The characteristics of several of its rules have contributed to inconsistencies with respect to degree of hazard attributed to common (particularly food-relevant) substances. This investigation examines these discrepancies, and their origins, raising awareness of such issues amongst users seeking to apply and/or adapt the rule-set.
A dataset of over 3000 compounds was assembled, each with Cramer class assignments issued by up to four groups of industry and academic experts. These were complemented by corresponding outputs from in silico implementations of the scheme present within Toxtree and OECD QSAR Toolbox software, including a working of a "Revised Cramer Decision Tree". Consistency between judgments was assessed, revealing that although the extent of inter-expert agreement was very high (≥97%), general concordance between expert and in silico calls was more modest (∼70%). In particular, 22 chemical groupings were identified to serve as prominent sources of disagreement, the origins of which could be attributed either to differences in subjective interpretation, to software coding anomalies, or to reforms introduced by authors of the revised rules.
This work was commissioned by the Threshold of Toxicological Concern (TTC) Task Force. For more information, click here.
Read the full article here
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