The Concept Paper discusses the need for conducting Human Intervention Studies for substantiating “Claims” for Food Products, Food ingredients including the nutrients as such but not limited to vitamins, minerals, amino acids, botanical extracts, herbs, spices, spice oleoresins and bioactive substances. It also provides guidance on important considerations for conducting Human Intervention Trials.
The Concept Paper Can Be Downloaded From: https://tinyurl.com/3c5mnub5
“Las buenas prácticas en el uso de grasas y aceites durante la preparación de alimentos son fundamentales para evitar la producción y consumo de grasas perjudiciales para la salud.”
Cell Reports Medicine, 2023
We provide a detailed review unfolding how the physiological and anatomical differences between the small and large intestine affect gut microbiota composition, function, and plasticity. This information is key to understanding how gut microbiota manipulation, including probiotic administration, may strain-dependently transform host-microbe interactions at defined locations.
Nutrition and Food Science, 2023
This is a systematic review on the effect of non-nutritive sweeteners on appetite, weight, glycemic regulation, and gut microbiome.
DOI: https://doi.org/10.1108/NFS-03-2023-0060
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Research on gut microbiota has generally focused on fecal samples, representing luminal content of the large intestine. However, nutrient uptake is restricted to the small intestine. Abundant immune cell populations at this anatomical site combined with diminished mucus secretion and looser junctions (partly to allow for more efficient fluid and nutrient absorption) also results in intimate host-microbe interactions despite more rapid transit. It is thus crucial to dissect key differences in both ecology and physiology between small and large intestine to better leverage the immense potential of human gut microbiota imprinting, including probiotic engraftment at biological sensible niches. Here, we provide a detailed review unfolding how the physiological and anatomical differences between the small and large intestine affect gut microbiota composition, function, and plasticity. This information is key to understanding how gut microbiota manipulation, including probiotic administration, may strain-dependently transform host-microbe interactions at defined locations.
This review focusses its narrative on the intimate relationship between the host and its bacterial constituents of the small and large intestine.
Dowload the full paper
or click on the images below to download the EG one-pager summary and graphical abstract
Commissioned by the Probiotics Task Force
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